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9789057022982

Using CNS Autopsy Tissue in Psychiatric Research: A Practical Guide

by ;
  • ISBN13:

    9789057022982

  • ISBN10:

    9057022982

  • Format: Hardcover
  • Copyright: 1999-03-25
  • Publisher: CRC Press

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Summary

Essential for the laboratory, this practical manual presents a wide variety of techniques associated with the use of human CNS tissue obtained at autopsy. The book contains detailed methodologies in discrete chapters written by an expert in the specific field. It also addresses the potential for extending molecular studies in brain tissue obtained at autopsy into studies in living brain by using neuroimaging techniques. In addition, the reader is directed to suppliers of equipment and reagents that have been shown to be useful when studying human brain tissue.Topics include problems of collecting brain tissue at autopsy, how psychiatric diagnosis can be made after death and specific problems faced in using human brain tissue in modern laboratory-based techniques.Suitable for all those using human tissue in their research, this manual is of particular value to those commencing studies using human brain tissue. Those involved in the study of brain tissue in an attempt to understand m

Table of Contents

Foreword vii
Contributors ix
The Collection of Tissue at Autopsy: Practical and Ethical Issues
1(18)
Deborah A. Kittell
Thomas M. Hyde
Mary M. Herman
Joel E. Kleinman
Psychiatric Diagnosis After Death: The Problems of Accurate Diagnosis from Case History Review and Relative Interviews
19(20)
Nicholas A. Keks
Christine Hill
Kenneth Opeskin
David L Copolov
Brian Dean
Membrane Binding Assays: Membrane Preparation and Assay Development
39(28)
Yogesh Dwivedi
Ghanshyam N. Pandey
The Localisation and Quantification of Molecular Changes in the Human Brain Using In Situ Radioligand Binding and Autoradiography
67(18)
Brian Dean
Geoffrey Pavey
Siew Yeen Chai
Frederick A. O. Mendelsohn
In Situ Hybridisation Histochemistry: Application to Human Brain Tissue
85(22)
Richard E. Loiacono
Andrew L. Gundlach
Immunohistochemistry Techniques Applicable for Use with Human Brain Tissue
107(20)
James Vickers
The Processing and Use of Postmortem Human Brain Tissue for Electron Microscopy
127(14)
Rosalinda C. Roberts
Lili Kung
Isolating Components of Human Brain: The Purification of Aβ and the Alzheimer's Amyloid Precursor Protein
141(18)
Robert A. Cherny
Colin L. Masters
Konrad Beyreuther
Ashley I. Bush
Analysis of Receptor Systems in Schizophrenia Using Tissue Obtained at Autopsy and Neuroimaging
159(16)
Janet Mulcrone
Brain Dean
Robert W. Kerwin
Index 175

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The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

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