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9780841239661

Polymers for Biomedical Applications

by
  • ISBN13:

    9780841239661

  • ISBN10:

    0841239665

  • Edition: 2nd
  • Format: Hardcover
  • Copyright: 2008-03-28
  • Publisher: American Chemical Society

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Summary

The aging of the "baby boomers" population and the focus on health issues continues to drive the demand for better medical devices and health care solutions. Significant developments over the last two decades particularly in the field of biomaterials have revolutionized the biomaterials-based health care industry. Polymers represent the largest and most promising class of biomaterials based on their wide spread use in various medical applications. A large number of polymeric biomaterials have been developed and new developments continue to appear in journals and patent literatures. Although several excellent books and reviews cover specific areas in this interdisciplinary field; not many books strive to cover a comprehensive overview to the wide applications of polymers in the medical industry. Also, due to the significant growth of research and new technological advancements in biomaterials, this creates a need for updated and revised books within few years. This book covers some of the recent research developments in the field of polymeric biomaterials and their biomedical applications with a particular emphasis on work presented in the symposium entitled "Polymers for Biomedical Applications". The Book starts with a review of the synthesis of new and improved biomaterials and continues with a survey of the various tools and characterization techniques that are being used to characterize the polymeric biomaterials. Later, specific applications are discussed; such as applications of polymers for controlled release of bioactive agents, reactive coatings for biological applications, scaffolds for tissue engineering and as a base material for development of medical devices and biosensors.

Table of Contents

Prefacep. xi
Polymers for Biomedical Applicationsp. 1
Synthesis of Biomaterials
From Drug-Eluting Stents to Biopharmaceuticals: Poly(ester amide) a Versatile New Bioabsorbable Biopolymerp. 10
Chitosan Water-Soluble System: An Approach to Prepare Superabsorbent Gelp. 27
The Cyclizationp. 37
High-Strength, Melt Processable, Aromatic Poly(anhydride)sp. 51
Fluorescently Labeled Protein-Polymer Bioconjugates Using Protein-Derived Macroinitiators from Living Radical Polymerizationp. 78
Adapting Polymeric Metal Complexes for Biomedical Applicationsp. 95
Characterization of Polymeric Biomaterials
Beyond Trial and Error: Tools to Advance the Engineering of Biomaterialsp. 118
Broadband Dielectric Spectroscopic Characterization of the Hydrolytic Degradation of Hydroxyl-Terminated Poly(D,L-lactide) Materialsp. 153
The Expanding Role of Mass Spectrometry as a Tool for Polymer Chemistryp. 170
Polymers for Drug Delivery
Synthesis and Properties of Functional Poly(vinylpyrrolidinone) Hydrogels for Drug Deliveryp. 196
Enzymatically Synthesized Pegylated Polymers as Nanomicellar Drug Delivery Systemsp. 204
Novel Two-Photon Activated Photodynamic Therapy Agents: Design, Synthesis, and Preclinical Studies on Subcutaneous Cancerous Tumorsp. 225
Synthesis and Characterization of Carborane Functionalized Dendronized Polymers as Potential Boron Neutron Capture Therapy Agentsp. 238
Biodegradable Ionomers for the Loading and Release of Proteins: Formation, Characterization, Mechanism, and Consequence of Water Uptakep. 250
Polymeric Surfaces
An Overview of the Biocompatibility of Polymeric Surfacesp. 268
Reactive Polymer Coatings for Biological Applicationsp. 283
Optimization of Microdomain Structure to Control Osteoblast Attachment on Poly(ethylene glycol)-Poly(caprolactone) Polyurethanesp. 299
Other Biomedical Applications
Polymers for Tissue Engineeringp. 310
Cell-Container Prepared with Cytocompatible Phospholipid Polymers for Cell and Tissue Engineeringp. 336
Evaluation of a Bioabsorbable Polyester Blend for Use in Medical Devices: CRANIOSORB, a Novel Cranial Fixation Systemp. 346
Biopolymers for Biosensors: Polypeptide Nanotubes for Optical Biosensingp. 371
Indexes
Author Indexp. 393
Subject Indexp. 395
Table of Contents provided by Ingram. All Rights Reserved.

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